Archive for the ‘Diseases of the brain’ Category

Cerebral Aneurysma

Is it anerurisma brain?
Brain aneurysm is a disorder of the brain arteries, where there are weaknesses in the arterial lining, forming a bulge or lump-like balloons. Lump artery has a thinner layer compared with normal blood vessels, so that one day may rupture suddenly.

Anyone can suffer aneurysma?
In general strike adults two or more decades. Percentage reaches 5% of all adults. By comparison between the aneurysm rupture (rupture) and aneurysm rupture is not 5:3.

What causes aneurysms?
The main cause of aneurysms is still controversial. However, when compared with normal blood vessels, the aneurysm was found an abnormality of the lining of blood vessels consists of three layers: the layer of the tunica intima, media and adventitia. Aneurysm is thinning at the tunica media and tunica intima becomes more elastic this result in weakness in the blood vessels in the aneurysm so that blood vessels form a bulge under the pressure of the blood vessels. Aneurysm is estimated to cause congenital abnormalities, hypertension, embolism, infection, and trauma.

Aneurysm What symptoms?
Symptoms of aneurysms that have not been broken or intact (unruptur aneurysm) is very rarely found. Therefore difficult to find papa aneurysm patients with aneurysms that were still intact, but was found incidentally during radiology examinations performed for other diseases or during medical check up. Symptoms are felt more often caused due to aneurysm rupture, a severe headache that comes suddenly, convulsions, stiffness in the neck to decrease in consciousness. But some symptoms can be a warning (warning sign) of aneurysms, namely: the paralysis of the foot and hand movements, vision problems, the eyelids can not open all of a sudden, pain in the face, headache, or symptoms resembling the symptoms of a stroke.

How to find or diagnose the aneurysm?
Aneurysms can be diagnosed with certainty by using angiography, the examination of blood vessels using a catheter / tube is inserted into a vein and given a dye (contrast). Can also be found by using CT scan or MRI. The best thing is to angiography.

How aneurysm treatment?
with surgical intervention and intervention radiology techniques, depending on the size, shape and location of a brain aneurysm. Surgical clipping technique, using a pincer clip aneurysms aneurysm neck area. While intervention radiology techniques is to use a balloon catheter and insert or coil which can clog the aneurysm.

How prognosis aneurysms?
The prognosis is an estimate of healing a disease. The prognosis depends on the type of aneurysm, aneurysm (rupture or unruptur), aneurysm shape, location, time and handling time of the patient’s condition treatment (age, clinical symptoms, awareness and the presence of other diseases such as heart). The principle is found faster healing aneurysms have a good chance, therefore, routine medical examination is recommended

Brain Abscess

Brain abscess is a localized accumulation of pus in the brain.
Brain abscess is rare and could be a result of:
- The spread of infection in other parts of the head (eg teeth, nose or ears)
- Head injuries that penetrate into the brain
- Infection in other parts of the body, which spread through the blood.
Brain abscess can cause various symptoms, depending on the location.
Symptoms can include headache, nausea, vomiting, drowsiness, seizures, personality changes and symptoms of other disorders of brain function.

These symptoms can occur within a few days or several weeks.

Initially patients feel the fever and chills, but these symptoms could disappear when the body successfully ward off the infection.
The best examination to find the brain abscesses is CT scan or MRI.
Biopsy performed to rule out the possibility of a tumor or stroke and to determine the organism causing the abscess.

Treatment for a brain abscess is an antibiotic; the most commonly used are penicillin, metronidazole, nafsilin and sefalosporin (eg seftizoksim).
Antibiotics are usually continued until 4-6 weeks and a CT scan and MRI repeated every 2 weeks.

If antibiotics are not able to overcome this situation, then surgery to remove the pus.

Sometimes abscesses caused increased pressure and swelling in the brain.
This situation is very serious and can cause permanent brain damage, which was given corticosteroids and other drugs (eg mannitol) to reduce brain swelling and reduce the pressure inside the brain.

One is Alzheimer’s Disease On Brain

Alzheimer’s or called az-Zhai-me, a sort of disease decreased brain function is complex and progressive. Alzheimer’s disease rather than a kind of contagious disease.

Alzheimer’s disease is a condition in which the power of memory decline with someone so badly infected can not fend for themselves. Alzheimer’s disease rather than ‘childish old age’ is simply a process of aging. On the other hand, is a kind of health problem that is very painful and needs to be given attention.

Alzheimer classified into one of a kind nyanyuk (dementia) is characterized by a downturn in the conversation, Sanity, memory, considerations, changes in personality and behavior that are not controlled. This situation is very burdensome not only to the infected, even family members who care. Alzheimer’s disease that decreases the memory function is also explained intellectual and social functions of his penghidap. Usually, family members only come with people who are sick to see a doctor if they have not put up with symptoms of a sick person.

Until now, the real source of this disease is not known. However, he was not due to aging. However, scientists believe, he was associated with the formation and changes in nerve cells that normally become fibers.

Risk for Alzheimer’s, a disease that is synonymous with old people, increases with age. “Starting at age 65 years, someone has a risk of five per cent of this disease and this risk has doubled every five years,” said the expert Psikogeriatrik, Office of Medical Psychology, Faculty of University Malaya Medical Center (PPUM), Dr. Esther Ebeenezer.

Level of Alzheimer’s

Forgot put the car keys, took the tray of money, do not know to buy goods to the store, forget the phone number or dos drug is commonly eaten among some mild symptoms.

If the sick person forgot the sugar in the drink mix, salt in cooking or mixing means water is categorized as a simple level.

If the sick person is not able to do things like deal with the principles themselves, wrong with the situation around the house, does not recognize associates or immediate family members, he indicated that sick people are in a serious level.

Other signs

People affected by this disease can be aggressive, quick to anger and lose interest or hobby to interact ever interested. It is estimated that in about 1950 of approximately 2.5 million of the world population suffering from this disease. In 2000, people with Alzheimer’s disease is estimated to reach six billion people.

World Health Organization (WHO), estimates that more than one billion people over the age older than 60 years or 10 percent of the population suffering from Alzheimer’s (2003). This increase, there is more to do with the world’s population aging, increases a woman’s lifetime until the age of 80 years and 75 years for men. In addition, maintenance of better health, declining marriage rates, increased divorce and those who marry but not many children.

The sick who are in a simple and severe stages will show a strange behavior. Among other things, like the scream, gasp and follow wherever nurses to the toilet though.

In addition, people who are sick also hear the sound or whisper soft and seeing frightening images. All of this is indirectly given to the nurse mental distress because they had to take care of the sick ‘36 hours’ day.

People who are sick are also sometimes would walk over here without a cause, and their sleep patterns are also changing. People who are sick for more sleep during the day and awake at night.

In general, a sick man who was diagnosed with this disease have died from pneumonia or pneumonia. This is because, at that time a sick person can not perform any other activities.

The sad thing is that sick people do not understand what was happening to them and need help from others. The bad news is Alzheimer’s disease, can not be cured. However, the symptoms can still be controlled with medication.

The drugs were given at an early stage, can help patients such as cognitive memory, daily activities and behavior.

People at risk

* People with hypertension who reach the age of 40 years and over
* Person with diabetes
* Lack of exercise
* High cholesterol levels
* Factor descent – have families who suffer from this disease at the age of 50.

Creutzfeldt Know

Creutzfeldt-Jakob disease is a degenerative neurological disorder that is very rare and incurable.

Spongiform encephalopathy infectious disease is caused by prions, which are often referred to as prion diseases. Other prion diseases include Gerstmann-Sträussler syndrome-Scheinker (GSS), fatal familial insomnia and kuru in humans, as well as cattle spongiform encephalopathy commonly known as mad cow disease, chronic wasting disease (CWD) in deer, and scrapie in sheep.

Prions are believed to cause Creutzfeldt-Jakob disease at least 2 shows a stable conformations. Conformation in the native state, is water soluble and present in healthy cells. Until 2006, no known biological function. Other circumstances konformatif less water soluble and easily forms a protein aggregate.

People also can contract Creutzfeldt-Jakob disease through gene mutation (needs to be defined), which only occurs in 5-10% of all cases.

CJD prion is dangerous because it increases the protein from folding into a state of illness, which causes the increase of insoluble prions in affected cells. The mass of misfolded proteins disrupts cell function and cause death. Mutations in the gene for the prion protein folding can lead to mistakes mostly alpha-helical regions into beta pleated sheets. Changes in conformation disables the ability of the protein to undergo digestion. Once the prion is transmitted, the defective proteins invade the brain and are produced in the feedback loop is supported himself, causing exponential spread of prions, death within a few months, although some people known to live for ever 2 years.

Stanley B. Prusiner was awarded the Nobel Prize in Physiology or Medicine in 1997 for the discovery prionnya. More than 1 decade, University neuropathologist Laura Manuelidis Yale dubious explanation for the disease. In January 2007 he and his colleagues published an article in the Proceedings of the National Academy of Sciences and reported that they found a similar virus particles (but so far without finding nucleic acids) in less than 10% strains of scrapie-infected cells and in mouse cell strains infected agent of CJD from humans.